Nephrology Medical News about blood pressure;serum TSH level

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A cross-sectional survey of relationship between serum TSH level and blood pressure
Journal of Human Hypertension, 06/29/09

Liu D et al. – The prevalence of hypertension in subclinical hypothyroidism group was significantly higher than in euthyroid group in females. Change of thyroid-stimulating hormone (TSH) in normal range did not affect blood pressure.

Methods

Study of the relationship between different levels of TSH and blood pressure in pts with subclinical hypothyroidism and euthyroidism
Questionnaire survey for 1319 pts
Measurements of blood pressure, height, and body weight
Blood samples for serum TSH
Assessment of FT3 and FT4 if abnormal TSH
Pts classified as euthyroid group and subclinical hypothyroidism group
Euthyroid group: group A (TSH 0.3–0.99 mIU l-1), group B (TSH 1.0–1.9 mIU l-1) and group C (TSH 1.91–4.8 mIU l-1)

Results

Different levels of serum TSH had no relation with systolic blood pressure (SBP) and diastolic blood pressure (DBP)
Prevalence of hypertension in subclinical hypothyroidism group significantly higher than euthyroid group in females (41.3 vs 25.6%)
Risk of hypertension in subclinical hypothyroidism group significantly higher than that in euthyroid group after adjusted for age, gender, smoking status, HOMA-IR (homoeostasis model assessment of insulin resistance) and body mass index
Association stronger in females; no statistical significance in males
Within normal range of TSH, both SBP and DBP similar among the 3 groups
Prevalence and risk of hypertension also similar among the 3 groups

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