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Rostoker G et al. - In patients whose renal function deteriorated, the original Cockcroft and Gault formula, the BSA-modified Cockcroft and Gault formula, the abbreviated MDRD equation, and the Mayo Clinic Quadratic Equation gave a reliable estimates of the GFR slope, with an acceptable bias. In the subgroup of patients with an improvement in renal function, these creatinine-based formulas underestimated the gain of GFR although this may have less important clinical consequences.


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