Your Article Summary
See Latest ArticlesSevere Bone Marrow Failure Due to Valganciclovir Overdose After Renal Transplantation From Cadaveric Donors: Four Consecutive Cases
Transplantation Proceedings, 07/01/09
Ar MC et al. - Valganciclovir is an l-valyl ester pro-drug of ganciclovir that was initially used to treat cytomegalovirus (CMV)–associated retinitis in patients with human immunodeficiency virus. Currently, it is also indicated for the prevention of CMV disease in solid-organ transplantation. This report demonstrates the in vivo pharmacodynamics of valganciclovir overdose in terms of hematotoxicity in the setting of renal impairment. Valganciclovir, as its derivative ganciclovir, should be used cautiously in patients with renal impairment.
Related Articles
Randomized controlled trial comparing the effectiveness and safety of intranasal and intramuscular naloxone for the treatment of suspected heroin overdose
Addiction, 11/13/09
Relevance Score: 43%
Cardiac arrest with residual blindness after overdose of tessalon perles
The Journal of Emergency Medicine, 11/10/09
Relevance Score: 42%
Intravitreal loading injection of ganciclovir with or without adjunctive oral valganciclovir for cytomegalovirus anterior uveitis
Graefe's Archive for Clinical and Experimental Ophthalmology, 10/02/09
Relevance Score: 42%
How adolescents who cut themselves differ from those who take overdoses
European Child and Adolescent Psychiatry, 10/05/09
Relevance Score: 41%
Substance abuse diagnostic test for teens can also predict high risk sexual behavior
EurekAlert, 10/19/09
Relevance Score: 40%
Today in Pharmacology/kinetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Mycophenolate Mofetil Versus Enteric-Coated Mycophenolate Sodium After Simultaneous Pancreas-Kidney Transplantation
Transplantation Proceedings, 12/16/09
The Impact of Renal Allograft Function on Exposure and Elimination of Mycophenolic Acid (MPA) and Its Metabolite MPA 7-O-glucuronide
Transplantation, 12/16/09
A Randomized and Prospective Study Comparing Treatment With High-Dose Intravenous Immunoglobulin With Monoclonal Antibodies for Rescue of Kidney Grafts With Steroid-Resistant Rejection
Transplantation, 12/16/09
Today in Transplantation...keeping you current
Receive free subspecialty "5-minute updates" via email
Laparoscopic-assisted vaginal radical hysterectomy (LAVRH) in recipients of kidney transplant with cervical cancer stage Ib1
Gynecological Surgery, 12/16/09
Mycophenolate Mofetil Versus Enteric-Coated Mycophenolate Sodium After Simultaneous Pancreas-Kidney Transplantation
Transplantation Proceedings, 12/16/09
The Impact of Renal Allograft Function on Exposure and Elimination of Mycophenolic Acid (MPA) and Its Metabolite MPA 7-O-glucuronide
Transplantation, 12/16/09