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Chen JS et al. - Tacrolimus concentrations are associated with CYP3A5 genotype. This study suggested to choose the initial dosage according to the CYP3A5 genotype to obtain a better outcome and reduce the incidences of acute rejection episodes and nephrotoxicity.

Today in Chronic Dz/Renal Failure...keeping you current

Management of HIV-Infected Patients With ESRD
Advances In Chronic Kidney Disease , 12/18/09

Renal Function Outcomes in Kidney Transplant Recipients After Conversion to Everolimus-Based Immunosuppression Regimen with CNI Reduction or Elimination
Transplantation Proceedings, 12/18/09

Hyperuricemia, Gout, and Renal Function After Liver Transplantation
Transplantation, 12/18/09

Today in Pharmacology/kinetics...keeping you current

Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma
Journal of Clinical Oncology, 12/18/09

Renal Function Outcomes in Kidney Transplant Recipients After Conversion to Everolimus-Based Immunosuppression Regimen with CNI Reduction or Elimination
Transplantation Proceedings, 12/18/09

Low-Dose Dopamine in Kidney Transplantation
Transplantation Proceedings, 12/18/09