Nephrology

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Improving outcomes in hypertensive patients: Focus on adherence and persistence with antihypertensive therapy
The Journal of Clinical Hypertension, 06/25/09

Elliott WJ et al. – A review on outcomes in hypertensive pts reports improved outcomes with a focus on adherence and persistence with antihypertensive therapy.

• Review on outcomes in hypertension

• Blood pressure (BP) control rates among treated pts in actual clinical practice are less than optimal despite effective BP control reducing risk of cardiovascular events in hypertension
• Costs of drugs and medical care are key but difficult to estimate both in clinical trials and general clinical practice
• Drug-taking behavior—adherence and persistence with antihypertensive regimens—influences BP control rates
• Rates vary greatly among antihypertensive classes based on many factors affecting pt adherence and persistence, including drug efficacy and tolerability
• Medications with fewer adverse effects associated with increased adherence and lower discontinuation rates
• Widespread use of these drugs (and generic or low-cost formulations) may lead to better long-term BP control and fewer cardiovascular events

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