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Takakura A et al. - The data demonstrate, for the first time, a role for polycystin-1 in kidney injury and repair and indicate that renal injury constitutes a ‘third hit’ resulting in rapid cyst formation in adulthood.

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Today in Cystic Dz...keeping you current

Echocardiographic findings in kidney transplant patients with autosomal dominant polycystic kidney disease
Scandinavian Journal of Urology and Nephrology, 12/04/09

Genotype–phenotype correlations in fetuses and neonates with autosomal recessive polycystic kidney disease
Kidney International, 11/30/09

Cystin Localizes to Primary Cilia via Membrane Microdomains and a Targeting Motif
Journal of the American Society of Nephrology, 11/25/09