Your Article Summary
See Latest ArticlesOverweight is associated with improved cancer-specific survival in patients with organ-confined renal cell carcinoma
Journal of Cancer Research & Clinical Oncology, 06/24/09
Schrader AJ et al. - In a study to assess whether different body mass index (BMI) levels at the time of surgery had an effect on long-term prognosis of renal cell carcinoma (RCC) pts, being overweight was identified as an independent prognostic marker of improved tumor-specific survival in pts with organ-confined RCC.
Methods- 771 pts, with complete information about their BMI, who had undergone renal surgery for RCC were evaluated.
- Mean follow-up was 5.48 yrs.
- Underweight, normal weight, pre-obesity, and obesity were diagnosed in 4 (0.5%), 239 (31%), 356 (46.2%), and 172 (22.3%) RCC pts, respectively.
- Overweight (BMI >25) was significantly associated with younger age and positive nodal status, but not with tumor stage, grade, visceral metastasis, gender, histological subtype, or tumor-related symptoms.
- Overweight pts had a significantly lower risk of cancer-related death; their median 5-yr tumor-specific survival rate was 80% vs 72% for pts with a BMI <25.
- Subgroup analysis revealed that the positive association between overweight and survival was even more pronounced in organ-confined RCC, but no correlation was observed in advanced disease.
Related Articles
Effect of Collecting Duct Histology on Renal Cell Cancer Outcome
The Journal of Urology, 11/18/09
Relevance Score: 83%
Prognostic Value of Capsular Invasion for Localized Clear-Cell Renal Cell Carcinoma
European Urology, 11/10/09
Relevance Score: 83%
Multidisciplinary treatment including sorafenib stabilized the bone metastases of renal cell carcinoma in an immunosuppressed renal transplant recipient
International Journal of Clinical Oncology, 10/30/09
Relevance Score: 83%
Prognostic factors for renal cell carcinoma: Trakya University experience from Turkey
European Journal of Cancer Care, 10/22/09
Relevance Score: 83%
The Expression of Thrombospondin-1 and p53 in Clear Cell Renal Cell Carcinoma: Its Relationship to Angiogenesis, Cell Proliferation and Cancer Specific Survival
The Journal of Urology, 10/14/09
Relevance Score: 83%
Today in Hematology/Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Birt-Hogg-Dube syndrome: diagnosis and management
The Lancet Oncology, 12/04/09
Evaluating Overall Survival and Competing Risks of Death in Patients With Localized Renal Cell Carcinoma Using a Comprehensive Nomogram
Journal of Clinical Oncology, 12/04/09
External Validation of the Mayo Clinic Stage, Size, Grade, and Necrosis (SSIGN) Score for Clear-Cell Renal Cell Carcinoma in a Single European Centre Applying Routine Pathology
European Urology, 12/04/09