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Advani A et al. - The predominant expression of the (P)RR at the apex of acid-secreting cells in the collecting duct, along with its colocalization and homology with an accessory protein of the vacuolar H+-ATPase, suggests that the (P)RR may function primarily in distal nephron H+ transport, recently noted to be, at least in part, an angiotensin II–dependent phenomenon.

Today in Basic Science/Genetics...keeping you current

Susceptibility genes in common complex kidney disease
Current Opinion in Nephrology and Hypertension, 12/17/09

Paracrine/endocrine mechanism of stem cells on kidney repair: role of microvesicle-mediated transfer of genetic information
Current Opinion in Nephrology and Hypertension, 12/17/09

The Changing Phenotype of Academic Nephrology— A Future at Risk
Clinical Journal of the American Society of Nephrology, 12/15/09