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See Latest ArticlesAmplification of the Pressure Pulse in the Upper Limb in Healthy, Middle-Aged Men and Women
Hypertension, 06/24/09
Segers P et al. - In healthy middle-aged subjects, the central-to-radial amplification of the pressure pulse is substantial. Amplification is higher in men than in women, decreases with age, and is primarily associated with the carotid augmentation index.
Patrick Segers, 06/24/09
| Pressure amplifcation was assessed from direct carotid, brachial and radial tonometry, independent of the use of a pressure transfer function, and following a calibration scheme assuming eaqual mean and diastolic blood pressure in the large arteries. Dataset used was our Asklepios population, a single-center single-operator database acquired in >2500 men and women aged 35-55 and free from overt cardiovascular disease. Our data confirm previous findings of McEniery et al., although the level of amplification is less than previously reported, probably due to the use of different methodologies and tonometer calibration. The consequence of pressure amplification is that brachial blood pressure not necessarily reflects central blood pressure. On the other hand, as amplification decreases with age, the difference between brachial and central blood pressure might not be too important in most patient populations. |
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