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Pore-forming toxins activate MAPK p38 by causing loss of cellular potassium
Biochemical and Biophysical Research Communications, 06/23/09
Kloft N et al. - Mitogen activated protein kinase (MAPK) p38 has emerged as a survival protein in cells that are attacked by bacterial toxins forming small membrane pores. The authors propose that PFT trigger the p38 MAPK-pathway by causing loss of cellular K+.
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