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A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study
Journal of Diabetes and its Complications, 06/25/09

Zhang D et al. - The present study thus provides the first evidence that SNP -11377C/G alters the sequence in one of the SP1 binding sites in the adiponectin promoter region. This polymorphism, together with another promoter SNP -11391G/A, may confer susceptibility to the development of DN in T1D patients among the GoKinD population.

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