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The long term label retaining population of the renal papilla arises through divergent regional growth of the kidney
American Journal of Physiology: Renal Physiology, 06/18/09
Adams DC et al. - The authors propose that selective papillary retention of BrdU arises through a combination of regionalized slowing of, and exit from, the cell cycle within the papilla during the period of ongoing kidney development, and extensive proliferative growth of the juvenile kidney resulting in dilution of BrdU below the detection level in extra-papillary regions.
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