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See Latest ArticlesGenetic basis of renal cellular dysfunction and the formation of kidney stones
Urological Research - Urolithiasis, 06/17/09
Khan SR et al. - Cellular impairment or dysfunction affects the supersaturation, by influencing the excretion of participating ions such as calcium, oxalate and citrate and causing hypercalciuria, hyperoxaluria or hypocitraturia. The production and excretion of macromolecular promoters and inhibitors of crystallization is also dependent upon proper functioning of the renal epithelial cells. Insufficient or ineffective crystallization modulators such as osteopontin, Tamm-Horsfall protein, bikunin, etc. are most likely produced by the impaired cells.
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Today in Chronic Dz/Renal Failure...keeping you current
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The Role of the Mammalian Target Of Rapamycin (mTOR) in Renal Disease
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Today in Stone Disease...keeping you current
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