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Hypophosphatemia: the common denominator of all rickets
Journal of Bone and Mineral Metabolism, 06/09/09
Tiosano D et al. - This review shows the role of phosphorous metabolism, transport and function in maintaining phosphorous supply to the growth plate, bone osteoblast and the kidney. Given that phosphorous is the common denominator of all rickets, this review proposes a new classification for the differential diagnosis of rickets, which is based on the mechanisms leading to hypophosphatemia—high PTH activity, high FGF23 activity or renal phosphaturia.
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