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See Latest ArticlesProfiling of anti-fibrotic signaling by hepatocyte growth factor in renal fibroblasts
Biochemical and Biophysical Research Communications, 06/05/09
Schievenbusch S et al. - The present study provides evidence that HGF stimulation of renal fibroblasts results in the activation of both the Erk1/2 and the Akt pathways. Functional cluster analyses and quantitative PCR assays indicate that the HGF-stimulated pathways transfer the anti-fibrotic effects in renal interstitial fibroblasts by reducing expression of extracellular matrix proteins, various chemokines, and members of the CCN family.
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Paracrine/endocrine mechanism of stem cells on kidney repair: role of microvesicle-mediated transfer of genetic information
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