Nephrology

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Familial hyperkalemia and hypertension: pathogenetic insights based on lithium clearance
Journal of Clinical Endocrinology and Metabolism, 06/16/09

Mayan H et al. - Hypercalciuria in FHHt seems to be dependent on urinary sodium. According to molecular studies, FHHt patients are presumed to have increased distal nephron sodium reabsorption, and therefore decreased proximal reabsorption of sodium, lithium and calcium. The observed decreased lithium clearance reflects probable abnormal renal handling of lithium, i.e. distal nephron lithium reabsorption. Therefore, hypercalciuria may result from proximal nephron aberration. Finally, earlier appearance of hypertension in males may be the result of sex-hormones activity.

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Systematic Review: Sodium Bicarbonate Treatment Regimens for the Prevention of Contrast-Induced Nephropathy
Annals of Internal Medicine, 11/03/09

New aspects in the pathogenesis, prevention, and treatment of hyponatremic encephalopathy in children
Pediatric Nephrology, 11/11/09

Does Concomitant Administration of Sevelamer and Calcium Carbonate Modify the Control of Phosphatemia
Therapeutic Apheresis and Dialysis, 11/04/09

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Choosing among renin-angiotensin system blockers for the management of hypertension: from pharmacology to clinical efficacy
Current Medical Research and Opinion, 11/20/09

A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial
The Lancet, 10/27/09

Comparative efficacy and safety of amlodipine/benazepril combination therapy and amlodipine monotherapy in severe hypertension
Journal of Human Hypertension, 11/10/09

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