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Prevalence of methylenetetrahydrofolate gene (MTHFR) C677T polymorphism among chronic hemodialysis patients and its association with cardiovascular disease: a cross-sectional analysis
Clinical and Experimental Nephrology, 05/28/09
Ibrahim S et al. - In the dialysis population that the authors studied, MTHFR C677T gene polymorphism occurred in a pattern similar to that seen for age- and gender-matched healthy controls. No significant association was detected between the T/T genotype and CVD in dialysis patients. Plasma total homocysteine levels were not affected by mutation of the gene coding for MTHFR, and this may be explained by the normal serum folate and vitamin B12 levels found in the study group.
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