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The Mesangial Cell Revisited: No Cell Is an Island
Journal of the American Society of Nephrology, 05/27/09
Schlondorff D et al. - The existence of cytokine cross-talk seems very likely, given the observations that podocyte injury frequently results in mesangial cell proliferation, whereas mesangial cell injury leads to foot process fusion and proteinuria. Another potentially fruitful area of future research is the role of mesangial cells as local modulators of innate and adaptive immune responses.
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