Nephrology Medical News about Losartan

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Reduction of microalbuminuria by using losartan in normotensive patients with type 2 diabetes mellitus: A randomized controlled trial
Saudi Journal of Kidney Diseases and Transplantation, 05/07/09

Agha A et al. - Losartan, an ARB, demonstrated significant anti-albuminuric ability in normotensive patients with T2DM with early nephropathy independent of hypertension. Losartan was well tolerated in the study with desirable anti albuminuric effects. The authors recommend that further large-scale long-term prospective placebo controlled clinical trials should be done in normotensive diabetic patients using ARBs. More evidence is needed to advocate early start of these drugs in T2DM patients with normal blood pressures in order to prevent morbidity and mortality associated with diabetic nephropathy.

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Efficacy and Safety of Losartan in Treatment of Hyperuricemia and Posttransplantation Erythrocytosis: Results of a Prospective, Open, Randomized, Case-Control Study
Transplantation Proceedings, 11/20/09 Relevance Score: 87%

Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial
The Lancet - Early Online Publication, 11/18/09 Relevance Score: 87%

Effect of losartan on ambulatory short-term blood pressure variability and cardiovascular remodeling in hypertensive patients on hemodialysis
Atherosclerosis, 11/13/09 Relevance Score: 87%

Recoverability of Renal Function After Relief of Chronic Partial Unilateral Ureteral Obstruction: Study of the Effect of Angiotensin Receptor Blocker (Losartan)
Urology, 10/28/09 Relevance Score: 87%

Loeys-Dietz syndrome: a Marfan-like syndrome associated with aggressive vasculopathy
Singapore Medical Journal, 11/11/09 Relevance Score: 84%