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See Latest ArticlesAntenatal Bartter's syndrome with sensorineural deafness
Indian Journal of Nephrology, 05/06/09
Bhamkar RP et al. - The authors report here the first case of a neonate with bilateral, sensorineural deafness, a variant of antenatal Bartter's syndrome from an Indian community. Close monitoring of serum creatinine, urinary prostaglandin, and serum indomethacin levels is mandatory to detect drug toxicity and response to therapy. The dose of indomethacin can then be titrated to achieve an adequate response. The indomethacin therapy has shown to decrease polyuria, renal salt-wasting, hyperprostaglandinuria, hypercalciuria, and nephrocalcinosis.
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