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Growth hormone treatment of infants with chronic kidney disease: requirement, efficacy, and safety
Pediatric Nephrology, 04/28/09
Haffner D et al. - Although their results were encouraging with respect to a sustained catch-up growth in rhGH-treated children, this issue has to be further addressed in prospective randomized controlled trials. In these trials special emphasis has to be given to the safety of this treatment modality, since rhGH might induce insulin resistance and glucose intolerance, especially in infants on high caloric intake and peritoneal dialysis.
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