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Linkage Analysis of Albuminuria
Journal of the American Society of Nephrology, 04/17/09
Mottl AK et al. - American Indians have a higher prevalence of albuminuria than the general population, likely resulting from a combination of environmental and genetic risk factors. To localize gene regions influencing variation in urinary albumin-to-creatinine ratio, the authors performed a linkage analysis and explored gene-by-diabetes, -hypertension, and -obesity interactions in a large cohort of American Indian families.
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