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Amore A et al. - The studies suggest a different therapeutic approach to proteinuric patients with nephropathies with different pathogenesis. In those with diabetesrelated CKD, studies such as RENAAL and INDT have produced evidence that ibersartan has a renoprotective effect due to the RAS system blockade, with a significant reduction of sclerotic evolution rate. Results were not confirmed by the DETAIL study, though.

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