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Heat shock response protects human peritoneal mesothelial cells from dialysate-induced oxidative stress and mitochondrial injury
Nephrology Dialysis Transplantation, 04/23/09
Kuo HT et al. - The acidic bioincompatible dialysates induce oxidative stress, {delta}{psi}m loss, and subsequent cell death in HPMCs. Amino acid dialysates is more biocompatible than glucose and icodextrin dialysates to HPMCs. Heat shock response protects HPMCs from the bioincompatible dialysates-induced cellular damage.
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