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See Latest ArticlesHigh aldosterone-to-renin variants of CYP11B2 and pregnancy outcome
Nephrology Dialysis Transplantation, 04/23/09
Escher G et al. - High aldosterone availability is associated with lower maternal blood pressure. In line with this observation, gain-of-function variants of the CYP11B2 reduce the risk of developing pre-eclampsia. Mutants of the mineralocorticoid receptor cannot explain the frequent syndrome of pre-eclampsia.
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