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See Latest ArticlesNew insights into phosphate homeostasis
British Journal of Renal Medicine, 04/01/09
Extracellular phosphate is crucial for many bodily functions, including skeletal development, energy metabolism, cell signalling and the regulation of protein synthesis. Body phosphate homeostasis is determined by the regulation of intestinal uptake of dietary phosphate, renal phosphate reabsorption and the exchange of phosphate between extracellular and bone storage pools. On a day-to-day basis, phosphate balance is achieved largely through the control of phosphate reabsorption in the proximal tubule: in the steady state, renal phosphate excretion reflects dietary intake, and daily urinary phosphate excretion correlates with its absorption from the diet.
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Does Concomitant Administration of Sevelamer and Calcium Carbonate Modify the Control of Phosphatemia
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