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Riley AM et al. - After aggressive treatment of infection, which included bilateral metatarsal amputation and subsequent left below-the-knee amputation as well as antibiotic administration for persistent osteomyelitis, the patient's renal function progressively improved with a reduction in serum creatinine concentration from 6.1 mg/dL to 2.7 mg/dL. On a 3-year follow-up evaluation, his serum creatinine concentration was 1.7 mg/dL and urine was negative for protein and blood.

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