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Keuleers S et al. - The present case suggests that vascular abnormalities may be caused by the genetic defect associated with ADPKD rather than with hypertension or ESRD, and supports previous assertions that there may be a direct association between ADKPD and arterial dissection. However, further research to elucidate the mechanisms of vascular degeneration and to identify the specific mutations responsible for the development of distinct vascular phenotypes in ADPKD is needed.

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