Nephrology

Your Article Summary

See Latest Articles

Comparative outcomes following endoscopic ureteral detachment and formal bladder cuff excision in open nephroureterectomy for upper urinary tract transitional cell carcinoma
The Journal of Urology, 02/10/09

Walton TJ et al. - In a study to compare differences after endoscopic ureteral detachment and open bladder cuff excision in nephroureterectomy, it was found that endoscopic ureteral detachment reduces operative duration and is associated with equivalent oncological outcomes compared with open bladder cuff excision in nephroureterectomy. Caution should be exercised in pts with low ureteral tumors.

• 138 pts underwent open nephroureterectomy for upper urinary tract transitional cell carcinoma with a median followup of 43 mos.
• Of these pts, 90 underwent endoscopic ureteral detachment and 48 underwent bladder cuff excision.
• Demographic, perioperative, and oncological outcome data were collected in all cases.
• Statistical analyses were performed using Student t test, chi-square, and log rank tests, and logistic and Cox regression.

• Mean operative duration was significantly lower in the endoscopic detachment group vs the bladder cuff group.
• There were 49 (54.4%) bladder recurrences in the endoscopic detachment group, of which 8 (16.3%) were muscle invasive and 3 (3.3%) developed at the resection site.
• There were 23 (47.9%) bladder recurrences in the bladder cuff group, of which 3 (13.0%) were muscle invasive and 2 (4.2%) developed at the resection site.
• All 5 resection site tumors occurred after excision of muscle invasive distal ureteral tumors and 4 of these had positive margins.
• There were no differences in recurrence-free survival or disease-specific survival.
• Operation subtype did not predict oncological outcome on univariate or multivariate analysis.

Today in Ureteral Disease...keeping you current

Receive free subspecialty "5-minute updates" via email

Effectiveness of Doxazosin in Treatment of Distal Ureteral Stones in Children
The Journal of Urology, 11/16/09

Patient position and semi-rigid ureteroscopy outcomes
International Braz J Urol, 11/03/09

Sonographic detection of renal and ureteral stones. Value of the twinkling sign
International Braz J Urol, 10/30/09

See All of Ureteral Disease