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See Latest ArticlesDNA Testing for Live Kidney Donors at Risk for Autosomal Dominant Polycystic Kidney Disease
Transplantation, 01/12/09
Huang E et al. - Radiographic imaging may be adequate to screen for kidney cysts in most at-risk donors but may fail to identify affected individuals younger than 40 years or older individuals from families with mild disease. Authors report a strategy that incorporates genetic testing in the evaluation of live kidney donors at risk for ADPKD whose disease status cannot be established with certainty on the basis of imaging studies alone. Authors show that DNA diagnostics can be used to enhance safe donation for certain living donor candidates at risk for ADPKD.
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