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Acid Loading In Vivo and Low pH in Culture Increase AT1 Receptor Expression in the Renal Cortex and Proximal Tubule Cells: Enhanced Response to Angiotensin II
American Journal of Physiology: Renal Physiology, 10/23/08
Nagami GT et al. - Results suggest that, after acid challenges, the enhanced ammoniagenic response of the proximal tubule to angiotensin II is, in part, mediated by increased AT1 receptor cell surface expression and that the enhancement of receptor expression plays an important role in the early response of the proximal tubule to acid challenges.
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