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See Latest ArticlesRetinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoter
American Journal of Physiology: Renal Physiology, 10/16/08
Islam MR et al. - The data indicate that induction of the PKD1 promoter by retinoic acid is mediated through Sp1 elements. RT-PCR showed that AT-RA treatment of HEK293T cells increased the levels of endogenous PKD1 RNA; and chromatin immunoprecipitation showed the presence of both RXR and Sp1 at the PKD1 proximal promoter. These results suggest that retinoids and their receptors may play a role in PKD1 gene regulation.
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Activation of p53 Promotes Renal Injury in Acute Aristolochic Acid Nephropathy
Journal of the American Society of Nephrology, 11/23/09
Torsades de Pointes induced by a combination of garenoxacin and disopyramide and other cytochrome P450, family 3, subfamily A polypeptide-4-influencing drugs during hypokalemia due to licorice
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Cystin Localizes to Primary Cilia via Membrane Microdomains and a Targeting Motif
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Today in Radiology/Diagnostics...keeping you current
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Measurement of kidney perfusion by magnetic resonance imaging: comparison of MRI with arterial spin labeling to para-aminohippuric acid plasma clearance in male subjects with metabolic syndrome
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