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See Latest ArticlesModifier Effect of the Glu298Asp Polymorphism of Endothelial Nitric Oxide Synthase Gene in Autosomal-Dominant Polycystic Kidney Disease
Nephron: Clinical Practice, 09/25/08
Stefanakis N et al. - The results suggested that the Glu298Asp polymorphism of NOS3 gene is associated with the onset age of ESRD. The distribution of C/T alleIes is significantly different between rapid and slow ADPKD progressors leading to the conclusion that the T allele of the Glu298Asp polymorphism of NOS3 gene is associated with earlier progression to ESRD in ADPKD patients.
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