Nephrology Medical News about Acid-Base Substrate Selectivity

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. 2008 Exclusive Survey—Earnings: Good news for primary care income

3. Medicare pay-for-reporting effort draws fire from frustrated doctors

4. Allopurinol-induced recurrent dress syndrome: Pathophysiology and treatment

5. Debunking Myths in the US Healthcare System

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Re-engineering of CYP2C9 to Probe Acid-Base Substrate Selectivity
Drug Metabolism and Disposition, 09/30/08

Tai G et al. - The data underscore the importance of the amino acid at position 108 in the acid substrate selectivity of CYP2C9, highlight the accommodating nature of the CYP2C9 active site, and provide a cautionary note regarding facile re-engineering of these complex cytochrome P450 active sites.

<< Previous
Increased risk of mortality in the elderly population with...

Next >>
Nitric Oxide Involvement in TNF-[alpha] and IL-1[beta]-Mediated...

The Blood-Brain Barrier Thyroxine Transporter Organic Anion-Transporting Polypeptide 1c1 Displays Atypical Transport Kinetics
Endocrinology, 10/14/09 Relevance Score: 45%%

Assessing acid–base disorders
Kidney International, 10/08/09 Relevance Score: 45%%

A Proteomic Approach To Identify Candidate Substrates of Human Adenovirus E4orf6-E1B55K and Other Viral Cullin-Based E3 Ubiquitin Ligases
Journal of Virology, 11/18/09 Relevance Score: 43%%

Acid–base balance: maintenance of plasma pH
Anaesthesia & intensive care medicine, 11/05/09 Relevance Score: 43%%

Acid-Base Balance in Peritoneal Dialysis Patients: A Stewart-Fencl Analysis
Renal Failure, 10/29/09 Relevance Score: 43%%