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Yu A et al. - The role of claudin-7 in ADPKD is to seal the paracellular route in Cl- secreting cyst epithelium, preventing backleak of Cl-, and that it thereby plays a permissive role in fluid secretion and cyst growth.

Today in Basic Science/Genetics...keeping you current

The Changing Phenotype of Academic Nephrology— A Future at Risk
Clinical Journal of the American Society of Nephrology, 12/15/09

Mapping of a new locus for congenital anomalies of the kidney and urinary tract on chromosome 8q24
Nephrology Dialysis Transplantation, 12/14/09

ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash, and immunologic manifestations in lupus patients with European ancestry
Annals of Rheumatic Diseases, 12/14/09

Today in Cystic Dz...keeping you current

Percutaneous Nephrolithotomy for Large or Multiple Upper Tract Calculi and Autosomal Dominant Polycystic Kidney Disease
The Journal of Urology, 12/16/09

Hemorrhagic Cystitis Secondary to Adenovirus or Herpes Simplex Virus Infection Following Renal Transplantation: Four Case Reports
Transplantation Proceedings, 12/15/09

Renal Cystic Diseases and Renal Neoplasms: A Mini-Review
Clinical Journal of the American Society of Nephrology, 12/14/09

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