Nephrology

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Uncoupling of ER-Mitochondrial Calcium Communication by Transforming Growth factor-{beta}
American Journal of Physiology: Renal Physiology, 07/24/08

Pacher P et al. - Down-regulation of both IP3R1 and IP3R3 was found in TGF-beta-treated PGASMC. Thus, TGF-beta causes uncoupling of mitochondria from the ER Ca2+ release. The sole source of this would be suppression of the IP3R-mediated Ca2+ efflux, indicating that the ER- mitochondrial Ca2+ transfer depends on the maximal rate of Ca2+ release. The impaired ER-mitochondrial coupling may contribute to the vascular pathophysiology associated with TGF-beta production.

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Small interference RNA targeting Kruppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo
Journal of Cancer Research & Clinical Oncology, 03/18/10

Successful treatment of steroid-resistant nephrotic syndrome associated with WT1 mutations
Pediatric Nephrology, 03/18/10

An Unexpected Counter-Regulatory Role of IL-10 in B-Lymphocyte-Mediated Transplantation Tolerance
American Journal of Transplantation, 03/12/10

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Randomized, Double-Blind, Controlled Study of Losartan in Children with Proteinuria
Clinical Journal of the American Society of Nephrology, 03/19/10

New mutation in female patient with renal variant of Fabry disease and HIV
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Targeting of renal proximal tubule Na,K-ATPase by salt-inducible kinase
Biochemical and Biophysical Research Communications, 03/18/10

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