nephrologylinx Medical News about Nephrin binds to the C-terminal

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Article Summary

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Nephrin binds to the C-terminal of a large-conductance calcium-activated potassium channel isoform and regulates its expression on the cell surface
American Journal of Physiology: Renal Physiology, 05/16/08

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Kim EY et al. - Nephrin plays a role in organizing the surface expression of ion channel proteins in podocytes, and may play a role in outside-in signaling to allow podocytes to adapt to mechanical or neurohumoral stimuli originating in neighboring cells.

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