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Urinary Concentration Defects and Mechanisms Underlying Nephronophthisis
Kidney and Blood Pressure Research, 05/06/08
Krishnan R et al. - The cystic kidney disease nephronophthisis (NPHP) is the commonest genetic cause of end-stage renal failure in young people and children. Understanding the cellular mechanisms underlying NPHP and other cystic kidney diseases will provide the rationale for therapeutic interventions in this disease. Early urinary concentration defects provide both a clue to clinical diagnosis of NPHP and potential therapeutic targets for pharmacological treatment of this condition.
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Today in Chronic Dz/Renal Failure...keeping you current
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Cholecalciferol Supplementation Alters Calcitriol-Responsive Monocyte Proteins and Decreases Inflammatory Cytokines in ESRD
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Today in Cystic Dz...keeping you current
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Loss of Oriented Cell Division Does not Initiate Cyst Formation
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Mitochondrial Autophagy Promotes Cellular Injury in Nephropathic Cystinosis
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