nephrologylinx Medical News about Glomerular angiotensinogen protein

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Article Summary

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Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy
Pediatric Nephrology, 05/06/08

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Free Abstract

Takamatsu M et al. - These data suggest that activated glomerular AGT expression is likely involved in elevated local ang II production and, thereby, may contribute to increased TGF-beta production and development of glomerular injury in IgAN. Augmentation of GEC-AGT production with ang II stimulation might drive further glomerular injury in a positive-feedback loop.

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