Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Allopurinol-induced recurrent dress syndrome: Pathophysiology and treatment 5. Debunking Myths in the US Healthcare System
Top Ten Searches
aldosteronism contrast dialysis vitamin d bicarbonate arf amyloidosis hypocalcemia renal artery husYour Article Summary
See Latest ArticlesSmall-Molecule CFTR Inhibitors Slow Cyst Growth in Polycystic Kidney Disease
Journal of the American Society of Nephrology, 04/14/08
Yang B et al. - Cyst expansion in polycystic kidney disease (PKD) involves progressive fluid accumulation, which is believed to require chloride transport by the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Herein is reported that small-molecule CFTR inhibitors of the thiazolidinone and glycine hydrazide classes slow cyst expansion in in vitro and in vivo models of PKD.
Related Articles
Brain permeable small molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha synuclein-induced toxicity
Journal of Pharmacology and Experimental Therapeutics, 12/07/09
Relevance Score: 65%
Development of histone deacetylase inhibitors as therapeutics for neurological disease
Future Neurology, 11/24/09
Relevance Score: 64%
p53 regulates LIF expression in human medulloblastoma cells
Journal of Neuro-Oncology, 11/19/09
Relevance Score: 64%
A small molecule inhibitor of XIAP induces apoptosis and synergises with vinorelbine and cisplatin in NSCLC
British Journal of Cancer, 11/13/09
Relevance Score: 64%
Overexpression of cell division cycle 7 homolog is associated with gene amplification frequency in breast cancer
Human Pathology, 11/12/09
Relevance Score: 64%
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Corticosteroid-induced kidney dysmorphogenesis is associated with deregulated expression of known cystogenic molecules, as well as indian hedgehog
American Journal of Physiology: Renal Physiology, 12/14/09
Mapping of a new locus for congenital anomalies of the kidney and urinary tract on chromosome 8q24
Nephrology Dialysis Transplantation, 12/14/09
ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash, and immunologic manifestations in lupus patients with European ancestry
Annals of Rheumatic Diseases, 12/14/09
Today in Cystic Dz...keeping you current
Receive free subspecialty "5-minute updates" via email
Renal Cystic Diseases and Renal Neoplasms: A Mini-Review
Clinical Journal of the American Society of Nephrology, 12/14/09
Loss of Oriented Cell Division Does not Initiate Cyst Formation
Journal of the American Society of Nephrology, 12/10/09
Mitochondrial Autophagy Promotes Cellular Injury in Nephropathic Cystinosis
Journal of the American Society of Nephrology, 12/09/09
Article Search
Sponsor