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Standard versus High-Dose CVVHDF for ICU-Related Acute Renal Failure
Journal of the American Society of Nephrology, 03/14/08

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Tolwani AJ et al. - The effect of dosage of continuous venovenous hemodiafiltration (CVVHDF) on survival in patients with acute renal failure (ARF) is unknown. In this study, 200 critically ill patients with ARF were randomly assigned to receive CVVHDF with prefilter replacement fluid at an effluent rate of either 35 ml/kg per h (high dosage) or 20 ml/kg per h (standard dosage).

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