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Article Summary

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Acid-Base Analysis: A Critique of the Stewart and Bicarbonate-Centered Approaches
American Journal of Physiology: Renal Physiology, 01/11/08

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Free Abstract

Kurtz I et al. - Our analysis demonstrates that: 1) while the principle of electroneutrality plays a central role in the strong ion formulation, electroneutrality per se does not dictate a specific [H+] and 2) the strong ion and bicarbonate-centered approaches are quantitatively identical; however, only the bicarbonate-centered approach reflects the underlying mechanistic acid-base phenomenology

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