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Article Summary

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Autosomal Dominant Polycystic Kidney Disease: Recent Advances in Pathogenesis and Treatment
Nephron: Physiology, 12/14/07

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Chang, M-Y, et al. - The identification of PKD1 and PKD2 together with the drive to elucidate the functions of their encoded proteins, polycystin-1 (PC1) and polycystin-2 (PC2), has led to an explosion of clinical and scientific interest in this common disorder. The aim of this review is to highlight recent advances in our understanding of ADPKD pathogenesis which are leading to exciting new treatment strategies

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