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EP2 Receptor Mediates PGE2-Induced Cystogenesis of Human Renal Epithelial Cells
American Journal of Physiology: Renal Physiology, 08/30/07

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Free Abstract

Elberg, G., et al. - Autosomal dominant polycystic kidney disease (ADPKD) is characterized by formation of cysts from tubular epithelial cells. Previous studies indicate that secretion of prostaglandin E2 (PGE2) into cyst fluid and production of cAMP underlie cyst expansion

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