BRG1 Increases Transcription of Proinflammatory Genes in Renal Ischemia Naito M et al. - Acute kidney injury stimulates renal production of inflammatory mediators, including TNF-alpha and monocyte chemoattractant protein 1 (MCP-1). BRG1 promotes increased transcription of TNF-alpha and MCP-1 by the proximal tubule in response to renal ischemia. [more...]