MPO-ANCA associated crescentic glomerulonephritis with numerous immune complexes: case report
BMC Nephrology, 06/04/2012
Morizane R et al. – A 78–year–old man presented with rapidly progressive glomerulonephritis (RPGN) after a 7–year course of chronic proteinuria and hematuria with stable renal function. This case is unique in that type 3 membranoproliferative glomerulonephritis (MPGN) and myeloperoxidase–Antineutrophil cytoplasmic antibody (ANCA)–associated crescentic glomerulonephritis (CGN) coexisted, and no similar case has been reported to date. Because ANCA–associated CGN has a predilection for elderly individuals and primary type 3 MPGN is rarely seen in this age group, coincidental existence appears less likely. This case may confer valuable information regarding the link between immune complex and ANCA–associated CGN.