Nephrology - Pharmacology/kinetics News & Articles

MDLinx Nephrology is the one place you can find the most updated medical journal articles that focus on topics such as: kidney function, renal replacement therapy, immunosuppression management, clinical pharmacology, chronic kidney disease and much more. The articles found on MDLinx are thoroughly classified and expertly summarized by our team of medical editors, and then ranked to provide you optimal value for your time.

As a bonus you can check out our “must read” articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from The Smartest Nephrologist daily quiz competition and review.

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Latest (4) Full Text Articles (107) Focus on Ureters

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121 Role of CXCR1 (CKR-1) in Inflammation of Experimental Mesangioproliferative Glomerulonephritis Renal Failure, March 18, 2013 Review Article

122 Phosphate binders, vitamin D and calcimimetics in the management of chronic kidney disease-mineral bone disorders (CKD-MBD) in children Pediatric Nephrology, March 15, 2013 Clinical Article

123 Combination of a Low Dose of Daclizumab and Standard Regimen for Prevention of Rejection in Men and Women Receiving a Kidney Transplant Iranian Journal of Kidney Diseases, March 15, 2013 Clinical Article

124 Impaired platelet P2Y12 inhibition by thienopyridines in chronic kidney disease: mechanisms, clinical relevance and pharmacological options Nephrology Dialysis Transplantation, March 14, 2013 Clinical Article

125 The safety and tolerability of regadenoson in patients with end-stage renal disease: The first prospective evaluation Journal of Nuclear Cardiology, March 14, 2013 Clinical Article

126 Nonsteroidal anti-inflammatory drug use is associated with cancer risk reduction in chronic dialysis patients Kidney International, March 14, 2013 Clinical Article

127 Anticoagulation With Fondaparinux for Hemodiafiltration in Patients With Heparin-Induced Thrombocytopenia: Dose-Finding Study and Safety Evaluation Artificial Organs, March 13, 2013 Clinical Article

128 Sodium Removal and Peritoneal Dialysis Modalities: No Differences With Optimal Prescription of Icodextrin Artificial Organs, March 13, 2013 Clinical Article

129 Cinacalcet Improves Endothelial Dysfunction and Cardiac Hypertrophy in Patients on Hemodialysis with Secondary Hyperparathyroidism Nephron Clinical Practice, March 13, 2013 Clinical Article

130 Antineutrophil cytoplasmic antibody-associated crescentic glomerulonephritis with membranous nephropathy treated using thiamazole Clinical and Experimental Nephrology Case Reports, March 13, 2013

131 Individualization of tacrolimus dosage basing on cytochrome P450 3A5 polymorphism - a prospective, randomized, controlled study Clinical Transplantation, March 13, 2013 Clinical Article

132 Effect of statin therapy on cardiovascular and renal outcomes in patients with chronic kidney disease: a systematic review and meta-analysis European Heart Journal, March 12, 2013 Evidence Based Medicine Review Article Clinical Article

133 A prediction of the renal and cardiovascular efficacy of aliskiren in ALTITUDE using short-term changes in multiple risk markers European Journal of Preventive Cardiology, March 12, 2013 Clinical Article

134 Safety and efficacy of liraglutide 1.2mg in patients with mild and moderate renal impairment: the ABCD nationwide liraglutide audit Practical Diabetes, March 12, 2013 Clinical Article

135 Long-Term Treatment of Hyperphosphatemia With Bixalomer in Japanese Hemodialysis Patients Therapeutic Apheresis and Dialysis, March 12, 2013 Clinical Article

136 Diffuse Proliferative Glomerulonephritis Associated With Cetuximab, an Epidermal Growth Factor Receptor Inhibitor American Journal of Kidney Diseases, March 12, 2013

137 Impact of the National Institutes of Health Focal Segmental Glomerulosclerosis (NIH FSGS) clinical trial on the treatment of steroid-resistant FSGS Nephrology Dialysis Transplantation, March 11, 2013 Clinical Article

138 Efficacy and Safety of Canagliflozin in Subjects With Type 2 Diabetes And Chronic Kidney Disease Diabetes, Obesity and Metabolism, March 8, 2013 Clinical Article

139 Decreased CD5+ B Cells in Active ANCA Vasculitis and Relapse after Rituximab Clinical Journal of the American Society of Nephrology, March 8, 2013 Clinical Article

140 Prevention of Recurrent Episodes of Rhabdomyolysis With Tacrolimus in a Transplant Recipient With Myopathy American Journal of Therapeutics, March 8, 2013 Clinical Article

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Clinical Pearls in Nephrology

In patients with acute myocardial infarction, the hazard ratio (HR) for major adverse cardiac and cerebrovascular events (MACCE) was highest in patients with chronic kidney disease and anemia.
Well-managed use of tobramycin long term is not associated with kidney failure. In a retrospective study among individuals with cystic fibrosis, the use of intravenous colistin, gentamicin, tobramycin or vancomycin did not correlate with increased BUN or creatinine after 8.5 years. Furthermore, only inhaled colistin correlated with kidney failure episodes
Evidence by the Study of Heart and Renal Protection trial showed cardiovascular benefit and absence of special safety concerns for statin administration in chronic kidney disease; yet some experts call for additional data on renal outcomes.

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Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

As published in the Journal of Infection, patients with community-acquired pneumonia (CAP) and acute cardiac events (ACEs) have a higher fatality rate (19.4%) than patients with CAP but without ACEs (6.4%). Of 3291 patients with CAP over a 15-year period, 315 had ACEs (8%; arrhythmias, n=199; congestive heart failure, n=118; myocardial infarction, n=30). Based on multivariate analysis, chronic heart disease, chronic kidney disease, tachycardia, septic shock, multilobar pneumonia, hypoalbuminemia, and pneumococcal pneumonia were associated with ACEs in patients with CAP.

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Serum amyloid A is a sensitive biomarker for advanced renal cancer

Researchers from Martin Luther University Halle-Wittenberg (Germany) have reported that serum amyloid A (SAA) has greater sensitivity in detecting advanced renal tumors than CRP or IL-6 levels. Specifically, the sensitivities and specificities of SAA, CRP, and IL-6 for advanced renal tumors were 78%, 69%, and 44%, and 82%, 82%, and 94%, respectively. Furthermore, the SAA levels were higher in patients with advanced renal tumors than patients with localized renal tumors.

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NSAID-associated AKI more severe in young children

As published in the Journal of Pediatrics, NSAID-associated acute tubular necrosis and acute interstitial nephritis occurred in 21 and 6 of 1015 children with acute kidney injuries, respectively. Correct dosing of NSAIDs was confirmed in 75% of the children. Children < 5 years of age had more severe disease, more often requiring dialysis (100% vs. 0) and ICU admission (75% vs. 9%), and increased length of stay (10 d vs. 7 d).

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Nephrology - Pharmacology/kinetics News & Articles

Articles

Clinical Pearls in Nephrology

Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

Serum amyloid A is a sensitive biomarker for advanced renal cancer

NSAID-associated AKI more severe in young children

Most Popular Nephrology Articles

Other Topics in Nephrology