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Nephrology - Pharmacology/kinetics News & Articles
MDLinx Nephrology is the one place you can find the most updated medical journal articles that focus on topics such as: kidney function, renal replacement therapy, immunosuppression management, clinical pharmacology, chronic kidney disease and much more. The articles found on MDLinx are thoroughly classified and expertly summarized by our team of medical editors, and then ranked to provide you optimal value for your time.
As a bonus you can check out our “must read” articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from The Smartest Nephrologist daily quiz competition and review.
Become a member and get exclusive access to Nephrology career opportunities, e-newsletters that keep you updated with the latest medical literature, Category 1 & 2 CME credit opportunities as well as the ability to earn honoraria by participating in Market Research studies.
Your Unread Messages in Nephrology
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Articles
Latest (3) Full Text Articles (107) Focus on Pediatric Nephrology121 Anticoagulation With Fondaparinux for Hemodiafiltration in Patients With Heparin-Induced Thrombocytopenia: Dose-Finding Study and Safety Evaluation Artificial Organs, March 13, 2013 Clinical Article
122 Sodium Removal and Peritoneal Dialysis Modalities: No Differences With Optimal Prescription of Icodextrin Artificial Organs, March 13, 2013 Clinical Article
123 Cinacalcet Improves Endothelial Dysfunction and Cardiac Hypertrophy in Patients on Hemodialysis with Secondary Hyperparathyroidism Nephron Clinical Practice, March 13, 2013 Clinical Article
124 Antineutrophil cytoplasmic antibody-associated crescentic glomerulonephritis with membranous nephropathy treated using thiamazole Clinical and Experimental Nephrology Case Reports, March 13, 2013
125 Individualization of tacrolimus dosage basing on cytochrome P450 3A5 polymorphism - a prospective, randomized, controlled study Clinical Transplantation, March 13, 2013 Clinical Article
126 Effect of statin therapy on cardiovascular and renal outcomes in patients with chronic kidney disease: a systematic review and meta-analysis European Heart Journal, March 12, 2013 Evidence Based Medicine Review Article Clinical Article
127 A prediction of the renal and cardiovascular efficacy of aliskiren in ALTITUDE using short-term changes in multiple risk markers European Journal of Preventive Cardiology, March 12, 2013 Clinical Article
128 Safety and efficacy of liraglutide 1.2mg in patients with mild and moderate renal impairment: the ABCD nationwide liraglutide audit Practical Diabetes, March 12, 2013 Clinical Article
129 Long-Term Treatment of Hyperphosphatemia With Bixalomer in Japanese Hemodialysis Patients Therapeutic Apheresis and Dialysis, March 12, 2013 Clinical Article
130 Diffuse Proliferative Glomerulonephritis Associated With Cetuximab, an Epidermal Growth Factor Receptor Inhibitor American Journal of Kidney Diseases, March 12, 2013
131 Impact of the National Institutes of Health Focal Segmental Glomerulosclerosis (NIH FSGS) clinical trial on the treatment of steroid-resistant FSGS Nephrology Dialysis Transplantation, March 11, 2013 Clinical Article
132 Efficacy and Safety of Canagliflozin in Subjects With Type 2 Diabetes And Chronic Kidney Disease Diabetes, Obesity and Metabolism, March 8, 2013 Clinical Article
133 Decreased CD5+ B Cells in Active ANCA Vasculitis and Relapse after Rituximab Clinical Journal of the American Society of Nephrology, March 8, 2013 Clinical Article
134 Prevention of Recurrent Episodes of Rhabdomyolysis With Tacrolimus in a Transplant Recipient With Myopathy American Journal of Therapeutics, March 8, 2013 Clinical Article
135 Efficacy and safety of alcohol sclerotherapy involving single-session multiple injections to treat simple renal cysts: a multicenter, prospective, randomized, controlled trial Full Text Chinese Medical Journal, March 7, 2013 Clinical Article
136 Long-Term Nephrotoxicity in Adult Survivors of Childhood Cancer Clinical Journal of the American Society of Nephrology, March 7, 2013 Clinical Article
137
Leflunomide for Inflammatory Arthritis in End-Stage Renal Disease on Peritoneal Dialysis: A Pharmacokinetic and Pharmacogenetic Study
Annals of Pharmacotherapy, March 6, 2013
Clinical Article
Exclusive Author Commentary
138 Clinical outcome with low-dose valacyclovir in high-risk renal transplant recipients: a 10-year experience Nephrology Dialysis Transplantation, March 6, 2013 Clinical Article
139 Tenofovir Use and Urinary Biomarkers Among HIV-Infected Women in the Womens Interagency HIV Study (WIHS) Journal of Acquired Immune Deficiency Syndromes, March 6, 2013 Clinical Article
140 Prospective Randomized Trial of Maintenance Immunosuppression With Rapid Discontinuation of Prednisone in Adult Kidney Transplantation American Journal of Transplantation, March 5, 2013 Clinical Article
Clinical Pearls in Nephrology
- In patients with acute myocardial infarction, the hazard ratio (HR) for major adverse cardiac and cerebrovascular events (MACCE) was highest in patients with chronic kidney disease and anemia.
- Well-managed use of tobramycin long term is not associated with kidney failure. In a retrospective study among individuals with cystic fibrosis, the use of intravenous colistin, gentamicin, tobramycin or vancomycin did not correlate with increased BUN or creatinine after 8.5 years. Furthermore, only inhaled colistin correlated with kidney failure episodes
- Evidence by the Study of Heart and Renal Protection trial showed cardiovascular benefit and absence of special safety concerns for statin administration in chronic kidney disease; yet some experts call for additional data on renal outcomes.
Highlights in Nephrology
Risk factors for acute cardiac events in patients with community-acquired pneumonia
As published in the Journal of Infection, patients with community-acquired pneumonia (CAP) and acute cardiac events (ACEs) have a higher fatality rate (19.4%) than patients with CAP but without ACEs (6.4%). Of 3291 patients with CAP over a 15-year period, 315 had ACEs (8%; arrhythmias, n=199; congestive heart failure, n=118; myocardial infarction, n=30). Based on multivariate analysis, chronic heart disease, chronic kidney disease, tachycardia, septic shock, multilobar pneumonia, hypoalbuminemia, and pneumococcal pneumonia were associated with ACEs in patients with CAP.
Read the article summarySerum amyloid A is a sensitive biomarker for advanced renal cancer
Researchers from Martin Luther University Halle-Wittenberg (Germany) have reported that serum amyloid A (SAA) has greater sensitivity in detecting advanced renal tumors than CRP or IL-6 levels. Specifically, the sensitivities and specificities of SAA, CRP, and IL-6 for advanced renal tumors were 78%, 69%, and 44%, and 82%, 82%, and 94%, respectively. Furthermore, the SAA levels were higher in patients with advanced renal tumors than patients with localized renal tumors.
Read the article summaryNSAID-associated AKI more severe in young children
As published in the Journal of Pediatrics, NSAID-associated acute tubular necrosis and acute interstitial nephritis occurred in 21 and 6 of 1015 children with acute kidney injuries, respectively. Correct dosing of NSAIDs was confirmed in 75% of the children. Children < 5 years of age had more severe disease, more often requiring dialysis (100% vs. 0) and ICU admission (75% vs. 9%), and increased length of stay (10 d vs. 7 d).
Read the article summaryMost Popular Nephrology Articles
Last month's top read Top Articles of 20121 Thiazide-Associated Hyponatremia: A Population-Based Study American Journal of Kidney Diseases, April 24, 2013
2 Cinacalcet Upregulates Calcium-Sensing Receptors of Parathyroid Glands in Hemodialysis Patients American Journal of Nephrology, April 9, 2013
3 Hemodialysis for the Treatment of Pulmonary Hemorrhage From Dabigatran Overdose American Journal of Kidney Diseases, April 19, 2013
4 Acute kidney injury: High-potency statin therapy and risk of acute kidney injury Nature Reviews Nephrology, April 10, 2013
5 The preventive effect of pentoxifylline on contrast-induced nephropathy: a randomized clinical trial International Urology and Nephrology, April 12, 2013
6 Intracutaneous sterile water injection versus oral paracetamol for renal colic during pregnancy: a randomized controlled trial International Urology and Nephrology, April 5, 2013
7 Use and safety of heparin-free maintenance hemodialysis in the USA Nephrology Dialysis Transplantation, April 8, 2013
8 Hyponatremia: an update on current pharmacotherapy Expert Opinion on Pharmacotherapy, April 15, 2013
9 Acute Kidney Injury During Vancomycin Therapy in Critically Ill Children Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, March 25, 2013
10 Cardiovascular Effects of Sevelamer in Stage 3 CKD Journal of the American Society of Nephrology, April 22, 2013
11 Dasatinib-Induced Nephrotic-Range Proteinuria American Journal of Kidney Diseases, March 29, 2013
12 Treatment of idiopathic membranous nephropathy with combination of low-dose tacrolimus and corticosteroids Journal of Nephrology, February 27, 2013
13 Randomized Controlled Trial of Enalapril on Decline in Glomerular Filtration Rate and Proteinuria in Children with Chronic Kidney Disease Indian Pediatrics, April 11, 2013 Free full text
14 Nicotinic Acid and Nicotinamide: A Review of Their Use for Hyperphosphatemia in Dialysis Patients Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 2, 2013 Review Article
15 Evolving therapeutic targets in renal cell carcinoma Current Opinion in Oncology, April 15, 2013
16 Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease Cochrane Reviews, April 1, 2013 Review Article
17 Long-term effects of prophylactic and therapeutic lamivudine treatments in hepatitis B surface antigen-positive renal allograft recipients Clinical and Experimental Nephrology, April 24, 2013
18 Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells British Journal of Cancer, April 18, 2013 Review Article
19 Cyclosporine versus mycophenolate mofetil for maintenance of remission of steroid-dependent nephrotic syndrome after a single infusion of rituximab European Journal of Pediatrics, April 1, 2013
20 Efficacy and Safety of Canagliflozin in Subjects With Type 2 Diabetes And Chronic Kidney Disease Diabetes, Obesity and Metabolism, March 8, 2013
Indexed Journals in Nephrology: Kidney International, Hemodialysis International, Nephrology Dialysis Transplantation more
Other Topics in Nephrology
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