Nephrology - Pharmacology/kinetics News & Articles

MDLinx Nephrology is the one place you can find the most updated medical journal articles that focus on topics such as: kidney function, renal replacement therapy, immunosuppression management, clinical pharmacology, chronic kidney disease and much more. The articles found on MDLinx are thoroughly classified and expertly summarized by our team of medical editors, and then ranked to provide you optimal value for your time.

As a bonus you can check out our “must read” articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from The Smartest Nephrologist daily quiz competition and review.

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Latest (4) Full Text Articles (107) Focus on Ureters

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

41 Eculizumab for Salvage Treatment of Refractory Antibody-Mediated Rejection in Kidney Transplant Patients: Case Reports Transplantation Proceedings, April 26, 2013 Clinical Article

42 Successful Treatment of Severe ABO Antibody-Mediated Rejection Using Bortezomib: A Case Report Transplantation Proceedings, April 26, 2013 Clinical Article

43 Effect of MDR1 Polymorphisms on the Blood Concentrations of Tacrolimus in Turkish Renal Transplant Patients Transplantation Proceedings, April 26, 2013 Clinical Article

44 Tacrolimus therapeutic drug monitoring in Tunisian renal transplant recipients: Effect of post-transplantation period Transplant Immunology, April 25, 2013 Clinical Article

45 Thiazide-Associated Hyponatremia: A Population-Based Study American Journal of Kidney Diseases, April 24, 2013 Clinical Article

46 Lipoprotein Kinetics in Male Hemodialysis Patients Treated with Atorvastatin Clinical Journal of the American Society of Nephrology, April 24, 2013 Clinical Article

47 Long-term effects of prophylactic and therapeutic lamivudine treatments in hepatitis B surface antigen-positive renal allograft recipients Clinical and Experimental Nephrology, April 24, 2013 Clinical Article

48 Evaluation of colestilan in chronic kidney disease dialysis patients with hyperphosphataemia and dyslipidaemia: a randomized, placebo-controlled, multiple fixed-dose trial Nephrology Dialysis Transplantation, April 23, 2013 Clinical Article

49 ADMA and C-reactive protein as mortality predictors in dialysis patients Central European Journal of Medicine, April 23, 2013 Clinical Article

50 Oral Paricalcitol Reduces the Prevalence of Posttransplant Hyperparathyroidism: Results of an Open Label Randomized Trial American Journal of Transplantation, April 23, 2013 Clinical Article

51 Cardiovascular Effects of Sevelamer in Stage 3 CKD Journal of the American Society of Nephrology, April 22, 2013 Clinical Article

52 Hemodialysis for the Treatment of Pulmonary Hemorrhage From Dabigatran Overdose American Journal of Kidney Diseases, April 19, 2013 Clinical Article

53 Breastfeeding and Tacrolimus: Serial Monitoring in Breast-Fed and Bottle-Fed Infants Clinical Journal of the American Society of Nephrology, April 19, 2013 Clinical Article

54 Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells British Journal of Cancer, April 18, 2013 Review Article

55 Use of High-Dose Ganciclovir for the Treatment of Cytomegalovirus Replication in Solid Organ Transplant Patients With Ganciclovir Resistance-Inducing Mutations Transplantation, April 18, 2013 Clinical Article

56 Impact of longitudinal exposure to mycophenolic acid on acute rejection in renal-transplant recipients using a joint modeling approach Pharmacological Research , April 18, 2013 Clinical Article

57 Effects of CYP3A4 and CYP3A5 polymorphisms on tacrolimus pharmacokinetics in Chinese adult renal transplant recipients: a population pharmacokinetic analysis Pharmacogenetics and genomics, April 17, 2013 Clinical Article

58 Sunitinib induces cellular senescence via p53/Dec1 activation in renal cell carcinoma cells Cancer Science, April 16, 2013 Clinical Article

59 Hyponatremia: an update on current pharmacotherapy Expert Opinion on Pharmacotherapy, April 15, 2013 Clinical Article

60 Evolving therapeutic targets in renal cell carcinoma Current Opinion in Oncology, April 15, 2013 Clinical Article

50 available pages First Previous 3 4 5 6 7 8 9 10 11 12 Next Last

Clinical Pearls in Nephrology

In patients with acute myocardial infarction, the hazard ratio (HR) for major adverse cardiac and cerebrovascular events (MACCE) was highest in patients with chronic kidney disease and anemia.
Well-managed use of tobramycin long term is not associated with kidney failure. In a retrospective study among individuals with cystic fibrosis, the use of intravenous colistin, gentamicin, tobramycin or vancomycin did not correlate with increased BUN or creatinine after 8.5 years. Furthermore, only inhaled colistin correlated with kidney failure episodes
Evidence by the Study of Heart and Renal Protection trial showed cardiovascular benefit and absence of special safety concerns for statin administration in chronic kidney disease; yet some experts call for additional data on renal outcomes.

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Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

As published in the Journal of Infection, patients with community-acquired pneumonia (CAP) and acute cardiac events (ACEs) have a higher fatality rate (19.4%) than patients with CAP but without ACEs (6.4%). Of 3291 patients with CAP over a 15-year period, 315 had ACEs (8%; arrhythmias, n=199; congestive heart failure, n=118; myocardial infarction, n=30). Based on multivariate analysis, chronic heart disease, chronic kidney disease, tachycardia, septic shock, multilobar pneumonia, hypoalbuminemia, and pneumococcal pneumonia were associated with ACEs in patients with CAP.

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Serum amyloid A is a sensitive biomarker for advanced renal cancer

Researchers from Martin Luther University Halle-Wittenberg (Germany) have reported that serum amyloid A (SAA) has greater sensitivity in detecting advanced renal tumors than CRP or IL-6 levels. Specifically, the sensitivities and specificities of SAA, CRP, and IL-6 for advanced renal tumors were 78%, 69%, and 44%, and 82%, 82%, and 94%, respectively. Furthermore, the SAA levels were higher in patients with advanced renal tumors than patients with localized renal tumors.

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NSAID-associated AKI more severe in young children

As published in the Journal of Pediatrics, NSAID-associated acute tubular necrosis and acute interstitial nephritis occurred in 21 and 6 of 1015 children with acute kidney injuries, respectively. Correct dosing of NSAIDs was confirmed in 75% of the children. Children < 5 years of age had more severe disease, more often requiring dialysis (100% vs. 0) and ICU admission (75% vs. 9%), and increased length of stay (10 d vs. 7 d).

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Most Popular Nephrology Articles

Last month's top read Top Articles of 2012

1 Thiazide-Associated Hyponatremia: A Population-Based Study American Journal of Kidney Diseases, April 24, 2013

2 Cinacalcet Upregulates Calcium-Sensing Receptors of Parathyroid Glands in Hemodialysis Patients American Journal of Nephrology, April 9, 2013

3 Hemodialysis for the Treatment of Pulmonary Hemorrhage From Dabigatran Overdose American Journal of Kidney Diseases, April 19, 2013

4 Acute kidney injury: High-potency statin therapy and risk of acute kidney injury Nature Reviews Nephrology, April 10, 2013

5 The preventive effect of pentoxifylline on contrast-induced nephropathy: a randomized clinical trial International Urology and Nephrology, April 12, 2013

6 Intracutaneous sterile water injection versus oral paracetamol for renal colic during pregnancy: a randomized controlled trial International Urology and Nephrology, April 5, 2013

7 Use and safety of heparin-free maintenance hemodialysis in the USA Nephrology Dialysis Transplantation, April 8, 2013

8 Hyponatremia: an update on current pharmacotherapy Expert Opinion on Pharmacotherapy, April 15, 2013

9 Acute Kidney Injury During Vancomycin Therapy in Critically Ill Children Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, March 25, 2013

10 Cardiovascular Effects of Sevelamer in Stage 3 CKD Journal of the American Society of Nephrology, April 22, 2013

11 Dasatinib-Induced Nephrotic-Range Proteinuria American Journal of Kidney Diseases, March 29, 2013

12 Treatment of idiopathic membranous nephropathy with combination of low-dose tacrolimus and corticosteroids Journal of Nephrology, February 27, 2013

13 Randomized Controlled Trial of Enalapril on Decline in Glomerular Filtration Rate and Proteinuria in Children with Chronic Kidney Disease Indian Pediatrics, April 11, 2013 Free full text

14 Nicotinic Acid and Nicotinamide: A Review of Their Use for Hyperphosphatemia in Dialysis Patients Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 2, 2013 Review Article

15 Evolving therapeutic targets in renal cell carcinoma Current Opinion in Oncology, April 15, 2013

16 Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease Cochrane Reviews, April 1, 2013 Review Article

17 Long-term effects of prophylactic and therapeutic lamivudine treatments in hepatitis B surface antigen-positive renal allograft recipients Clinical and Experimental Nephrology, April 24, 2013

18 Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells British Journal of Cancer, April 18, 2013 Review Article

19 Cyclosporine versus mycophenolate mofetil for maintenance of remission of steroid-dependent nephrotic syndrome after a single infusion of rituximab European Journal of Pediatrics, April 1, 2013

20 Efficacy and Safety of Canagliflozin in Subjects With Type 2 Diabetes And Chronic Kidney Disease Diabetes, Obesity and Metabolism, March 8, 2013

Indexed Journals in Nephrology: Kidney International, Hemodialysis International, Nephrology Dialysis Transplantation more

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Nephrology - Pharmacology/kinetics News & Articles

Articles

Clinical Pearls in Nephrology

Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

Serum amyloid A is a sensitive biomarker for advanced renal cancer

NSAID-associated AKI more severe in young children

Most Popular Nephrology Articles

Other Topics in Nephrology