Nephrology - Basic Science/Genetics News & Articles

MDLinx Nephrology is the one place you can find the most updated medical journal articles that focus on topics such as: kidney function, renal replacement therapy, immunosuppression management, clinical pharmacology, chronic kidney disease and much more. The articles found on MDLinx are thoroughly classified and expertly summarized by our team of medical editors, and then ranked to provide you optimal value for your time.

As a bonus you can check out our “must read” articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from The Smartest Nephrologist daily quiz competition and review.

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Articles

Latest (2) Full Text Articles (108) Focus on Pediatric Nephrology

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 RAGE-mediated interstitial fibrosis in neonatal obstructive nephropathy is independent of NF-kB activation Kidney International, May 17, 2013 Review Article

2 Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury Kidney International, May 17, 2013 Review Article

Prior Articles

3 Vesicoureteral reflux: Association of TNXB mutations with vesicoureteral reflux Nature Reviews Nephrology, May 15, 2013 Review Article

4 CRM1 Blockade by Selective Inhibitors of Nuclear Export Attenuates Kidney Cancer Growth The Journal of Urology, May 15, 2013 Clinical Article

5 Prognostic significance of graft Foxp3 expression in renal transplant recipients: a critical review and attempt to reconcile discrepancies Nephrology Dialysis Transplantation, May 15, 2013 Review Article

6 Study of CC chemokine receptor 5 in renal allograft rejection Full Text Indian Journal of Nephrology, May 15, 2013 Review Article

7 Retrieval of kidney tissue for light microscopy from frozen tissue processed for immunofluorescence: A simple procedure to avoid repeat kidney biopsies Full Text Indian Journal of Nephrology, May 15, 2013

8 A high blood level in the venous chamber and a wet-stored dialyzer help to reduce exposure for microemboli during hemodialysis Hemodialysis International, May 14, 2013 Review Article

9 Genome-wide analysis of histone H3 lysine9 trimethylation by ChIP-seq in peripheral blood mononuclear cells of uremia patients Hemodialysis International, May 14, 2013 Review Article

10 Histone Deacetylase Inhibitor Enhances Recovery after AKI Journal of the American Society of Nephrology, May 13, 2013 Review Article

11 Suppression of titanium particle-induced TNF-alpha expression and apoptosis in human U937 macrophages by siRNA silencing The International Journal of Artificial Organs, May 13, 2013 Review Article

12 Renal CD133+/CD73+ Progenitors Produce Erythropoietin under Hypoxia and Prolyl Hydroxylase Inhibition Journal of the American Society of Nephrology, May 13, 2013 Review Article

13 Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension Journal of the American Society of Nephrology, May 13, 2013

14 Rheb/mTORC1 Signaling Promotes Kidney Fibroblast Activation and Fibrosis Journal of the American Society of Nephrology, May 13, 2013 Review Article

15 Scaffolding Proteins DLG1 and CASK Cooperate to Maintain the Nephron Progenitor Population during Kidney Development Journal of the American Society of Nephrology, May 13, 2013 Review Article

16 Mutation of the Mg2+ Transporter SLC41A1 Results in a Nephronophthisis-Like Phenotype Journal of the American Society of Nephrology, May 13, 2013 Review Article

17 A novel TRPC6 mutation in a family with podocytopathy and clinical variability Full Text BMC Nephrology, May 13, 2013

18 Immobilization of BMP-2 on a nano-hydroxyapatite-coated titanium surface using a chitosan calcium chelating agent The International Journal of Artificial Organs, May 13, 2013 Review Article

19 Extended characterization of a new class of membranes for blood purification: The high cut-off membranes The International Journal of Artificial Organs, May 13, 2013 Review Article

20 Increase in Skin Autofluorescence and Release of Heart-Type Fatty Acid Binding Protein in Plasma Predicts Mortality of Hemodialysis Patients Artificial Organs, May 10, 2013 Review Article

50 available pages FirstPrevious 1 2 3 4 5 6 7 8 9 10 Next Last

Clinical Pearls in Nephrology

In patients with acute myocardial infarction, the hazard ratio (HR) for major adverse cardiac and cerebrovascular events (MACCE) was highest in patients with chronic kidney disease and anemia.
Well-managed use of tobramycin long term is not associated with kidney failure. In a retrospective study among individuals with cystic fibrosis, the use of intravenous colistin, gentamicin, tobramycin or vancomycin did not correlate with increased BUN or creatinine after 8.5 years. Furthermore, only inhaled colistin correlated with kidney failure episodes
Evidence by the Study of Heart and Renal Protection trial showed cardiovascular benefit and absence of special safety concerns for statin administration in chronic kidney disease; yet some experts call for additional data on renal outcomes.

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Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

As published in the Journal of Infection, patients with community-acquired pneumonia (CAP) and acute cardiac events (ACEs) have a higher fatality rate (19.4%) than patients with CAP but without ACEs (6.4%). Of 3291 patients with CAP over a 15-year period, 315 had ACEs (8%; arrhythmias, n=199; congestive heart failure, n=118; myocardial infarction, n=30). Based on multivariate analysis, chronic heart disease, chronic kidney disease, tachycardia, septic shock, multilobar pneumonia, hypoalbuminemia, and pneumococcal pneumonia were associated with ACEs in patients with CAP.

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Serum amyloid A is a sensitive biomarker for advanced renal cancer

Researchers from Martin Luther University Halle-Wittenberg (Germany) have reported that serum amyloid A (SAA) has greater sensitivity in detecting advanced renal tumors than CRP or IL-6 levels. Specifically, the sensitivities and specificities of SAA, CRP, and IL-6 for advanced renal tumors were 78%, 69%, and 44%, and 82%, 82%, and 94%, respectively. Furthermore, the SAA levels were higher in patients with advanced renal tumors than patients with localized renal tumors.

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NSAID-associated AKI more severe in young children

As published in the Journal of Pediatrics, NSAID-associated acute tubular necrosis and acute interstitial nephritis occurred in 21 and 6 of 1015 children with acute kidney injuries, respectively. Correct dosing of NSAIDs was confirmed in 75% of the children. Children < 5 years of age had more severe disease, more often requiring dialysis (100% vs. 0) and ICU admission (75% vs. 9%), and increased length of stay (10 d vs. 7 d).

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Indexed Journals in Nephrology: Kidney International, Hemodialysis International, Nephrology Dialysis Transplantation more

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Nephrology - Basic Science/Genetics News & Articles

Articles

Prior Articles

Clinical Pearls in Nephrology

Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

Serum amyloid A is a sensitive biomarker for advanced renal cancer

NSAID-associated AKI more severe in young children

Most Popular Nephrology Articles

Other Topics in Nephrology